Dexamethasone is a corticosteroid that is used to treat different heath conditions like skin diseases, allergic disorder, asthma, brain swelling, rheumatic problems and arthritis.
This drug comes in different trade names like Decadron, Dexasone, Diodex, Hexadrol, Maxidex, DexPak, Zema-Pak, etc.. It reduces the defensive reaction of the body and reduces symptoms. It can be administered with antibiotics to treat tuberculosis.
Dexamethasone is administered to the body system through the following means:
Intravenous Therapy: When the medicine in liquid form, it’s administered to the body by delivery through the vein with the assistance of injections or as drips. This mode of administration is known to be the fastest as it goes straight to the bloodstream.
Intramuscular treatment: Otherwise known and abbreviated as IM. This drug delivery system is carried out by the aid of injection into the muscle.
Subcutaneous Injection Therapy: is one of the many system of drug administration. It’s abbreviated as SC and is used to administration dexamethasone through the subcutaneous layer of the skin.
Oral Administration: This entails administering dexamethasone through the mouth.
Dexamethasone Tablets USP generally contain either 0.5 mg, 0.75 mg, 1.5 mg, 2 mg, 4 mg, or 6 mg of dexamethasone USP. Each tablet also contain some inactive ingredients such as magnesium stearate, lactose, monohydrate, sugar, starch, FD&C Red, FD&C Yellow, Yellow Iron Oxide, D&C Yellow, and FD&C Blue.
Dexamethasone Oral Solution USP is formulated for oral administration contains 05.5 mg per 5 ml of dexamethasone USP. This oral solution contains some inactive ingredients such as propylene glycol, sorbitol solution, propylparaben, anhydrous citric acid, glycerin, disodium edetate and water.
USES OF DEXAMETHASONE/PROS
Dexamethasone has various uses in anti inflammatory diseases, cancer, endocrine therapy, pregnancy, high altitude illnesses, nausea and vomiting, sore throat, and veterinary applications.
Dexamethasone is combined with clotrimazole and marbofloxacin with a fresh name AURIZON as a remedy for severe earing infections especially in puppies.
Dexamethasone combined with dichlormethiazide may be used in the treatment of general swelling and bruising distal limbs in horses.
A single dose of dexamethasone in children reduces the swelling of the airway which in turns improves breathing and decreased discomfort. To put it differently, can be utilized for treating CROUP in children. Dexamethasone given in a high dose serves as a counteract to allergic anaphylactic shock, Dexamethasone intravitreal steroid implant was accepted by the Federal dental agency for the treatment of climatic conditions such as diabetic macular edema, central retinal vein occlusion, and uveitis, dexamethasone is present in ear drops, eye drops especially after eye surgery and present in nasal sprays. Dexamethasone is used to treat autoimmune and inflammatory diseases such as rheumatoid arthritis, Idiopathic thrombocytopenic purpura. Dexamethasone is given before and or after dental surgeries like the removal of the wisdom tooth. Dexamethasone can also be treated before antibiotics in case of bacterial meningitis to reduce inflammatory response to the killed bacterias.
In brain tumors, dexamethasone can be used to suppress the development of edema which can compress other brain structures if not attended to, dexamethasone can be used as a direct chemotherapeutic agent for the treatment of multiple myeloma.
Pregnancy complications may occur like premature delivery, but with the use of dexamethasone, it helps correct premature delivery by aiding in the maturation of the fetus’ lungs.
Nausea and vomiting
People who’ve had surgery experience nausea and vomiting. Administration of dexamethasone intravenously is effective for preventing nausea and vomiting from recurring.
Dexamethasone, like every other drugs has side effects they provide. The regular side effects from the ingestion of dexamethasone includes
Trouble in sleeping
Increase in appetite
But if the below listed serious side effects occur, contact your doctor as soon as you notice
Increased thirst and urination
Signs of infection like fever
Slow, fast or irregular heartbeat
For those who have a fungal infection or allergic to this drug, please don’t take it. Before taking dexamethasone, tell your doctor or pharmacist if you have:
Glaucoma or cataracts
High blood pressure
Herpes infection of the eyes
This medicine may mask signs of infection or put you at greater risk of developing very serious ailments. Report any injuries or signs of infection (e.g., persistent sore throat/fever/cough, pain during urination, muscle aches) that occur during treatment.
This medication may slow down a child’s growth if used for quite a while. Consult the doctor or pharmacist for more details. See the doctor regularly so that your child’s height and growth could be checked.
This drug may pass into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast- feeding.
An overdose of this medication does not pose any life-threatening issues. Long term use of high does may lead to thinning skin, increased acne or facial hair, loss of interest in sex, menstrual problems and impotence.
DRUGS THAT AFFECT DEXAMETHASONE
It’s not a fantastic safe to use some certain drugs in exactly the same time because they pose a lot of risks. Ensure you tell your doctor about all the drugs you are using before taking dexamethasone such as;
Insulin or diabetes medications
Birth control pills or hormone replacement therapy
Blood thinner — Coumadin, Jantoven
Antibiotic or antifungal medicine
Medicine to treat dementia or Parkinson disease
The activity of the world health organization in tagging dexamethasone as an essential drug in the health care field has revealed dexamethasone to be of significance to the health of man and research showing that surplus dexamethasone can cause hypertension through various mechanisms demonstrate that where there is great, there’s also bad. Moderation is the key to ensuring that more good than bad is what’s gotten from this drug. Following the physician’s prescription strictly and not self-medicating will also help to make dexamethasone us be of more good than bad.